Neprilysin Market Comprehensive Insight by Growth Rate, Industry Status, Forecast till 2027
The global neprilysin market is anticipated to grow at a significant CAGR during the forecast period (2021-2027). Neprilysin is a zinc-dependent metalloprotease. It cleaves peptides at the amino side of hydrophobic residues as well as inactivates several peptide hormones such as glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. The major factor driving the growth of the market is the rising prevalence of hypertension across the globe.
According to the World Health
Organization (WHO), in 2021, hypertension is a major cause of premature death
globally and an estimated 1.28 billion adults aged 30 years to 79 years have
hypertension with two-thirds living in low- and middle-income countries.
Additionally, as per the same source, an estimated 46% of adults with
hypertension are unaware that they have the condition and less than half of
adults or 42% with hypertension are diagnosed and treated. Furthermore,
approximately 1 in 5 adults or 21% with hypertension have it under control.
Hence, the increasing prevalence of hypertension is driving the demand for
neprilysin as it increases the bioavailability of natriuretic peptides (NPs),
bradykinin, and substance P which results in natriuretic, vasodilatatory, and
anti-proliferative effects.
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Some major players operating in
the market include Novartis International AG, Cipla Ltd., and Merck KGaA, among
others. The market players are contributing significantly to the growth of the
market by the adoption of various strategies including mergers &
acquisitions, geographical expansion, partnerships and collaborations, and new
product launches, to stay competitive in the market. For instance, in February
2021, Novartis announced that it has received approval for Entresto
(sacubitril/valsartan) from the US FDA. Entresto contains the neprilysin
inhibitor sacubitril and the angiotensin receptor blocker (ARB) valsartan and
is used to reduce the risk of cardiovascular death and hospitalization for
heart failure in adult patients with chronic heart failure.
Market Coverage
•
The market number available for – 2020-2027
•
Base year- 2020
•
Forecast period- 2021-2027
Segment Covered-
•
By Type
•
By Application
Regions Covered-
•
North America
•
Europe
•
Asia-Pacific
•
Rest of the World
Competitive Landscape- Novartis
International AG, Cipla Ltd., and Merck KGaA, among others
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Global Neprilysin Market Report by Segment
By Type
• TD-0714
• Sacubitril
• PL-265
• STR-324
• LHW-090
• Others
By Application
• Acute
Heart Failure
• Cancer
Pain
• Hypertension
• Alzheimer’s
Disease
• Other
Global Neprilysin Market Report by Region
North America
·
United States
·
Canada
Europe
·
UK
·
Germany
·
Spain
·
France
·
Italy
·
Rest of Europe
Asia-Pacific
·
India
·
China
·
Japan
·
South Korea
·
Rest of APAC
Rest of the World
·
Latin America
·
Middle East & Africa
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